Dr Stefan Hofer Surgery Case Study Photos


• Clinical Research Unit
• Clinical Studies Resource Centre
• Ontario Cancer Institute (OCI)

Dr. Hofer obtained his medical degree from the University of Amsterdam in 1992. He then completed his PhD studying tissue oxygen tension as an indicator of tissue perfusion in the Department of Surgical Research, Academic Medical Center, Amsterdam. He obtained his board certification in Plastic Surgery from the Netherlands in 2000 and became the first Plastic Surgeon to be awarded the highly prestigious Dutch Cancer Society clinical fellowship, which funded his one-year Microsurgery Research fellowship at the Bernard O’Brien Institute of Microsurgery at St. Vincent’s Hospital and the University of Melbourne in Melbourne, Australia. Dr. Hofer is internationally recognized for his outstanding contributions in the areas of clinical service, education, and research. Prior to becoming the Division's first international candidate to be recruited in over a decade, Dr. Hofer was an Associate Professor in the Department of Plastic and Reconstructive Surgery, Erasmus Medical Center, Rotterdam and the Head of Plastic and Reconstructive Surgical Oncology.

Areas of Specialty

Plastic & Reconstructive Surgical Techniques and Tissue Engineering, Microsurgery, Breast, Face, Head & Neck Reconstruction, Functional Restoration

Practice Hospital

Toronto General Hospital (UHN)




Katrina Aquino

Practice Location

UHN - Toronto General Hospital
N8-865, 200 Elizabeth St.
Toronto, Ontario
M5G 2C4


(416) 340-3449


(416) 340-4403

Referral Instructions
Research Interests

Innovative Surgical Techniques
My main clinical research interest is in the development, refinement and evaluation of innovative plastic & reconstructive surgical techniques for the face, head & neck and breast following oncology surgery. An example of the development and refinement of innovative flap procedures is the Deep Inferior Epigastric Perforator Flap (DIEP) breast reconstruction technique that involves dissection of the skin and fatty tissue in the abdomen to restore the breast mound while maintaining the integrity, function and strength of the donor abdominal site compared to other procedures.

Tissue Engineering
While my clinical research focuses on technical improvements of reconstructive techniques, I am also involved in tissue engineering of adipose tissue and mucosa using living cells in artificial supporting scaffolds to replace missing tissues. This is a technology that uses the patients’ own cells in the lab and transplants the engineered living tissue back into the body. We have developed a 3-dimensional tissue engineered mucosa substitute, which we use to study radiation effects. The ultimate goal of this research is to maximize the reconstructive outcomes and quality of life while minimizing the disability caused to the donor tissue sites.

Functional, Aesthetic and Quality of Life Outcomes
I have a strong interest in the functional, aesthetic and quality of life outcomes after reconstructive surgery and have received grant funding for research projects investigating these outcomes. In addition, I am developing prospective, outcomes databases for Breast Restoration as well as Head & Neck Cancer Reconstruction at UHN.

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Jul 13, 2009 12:14PMjennyc wrote:

I had a double mastectomy and immediate reconstruction six years ago. I also was unable to use my abd. and ended up doing the latiismus dorsi flap,without inplants. I have had a lot of problems with tightness, burning, tenderness, stabbing pain, numbness, ever since. My shoulder,esp. my right constantly aches, hard to move, they both get tired quickly. I do not believe there has been a long term study done to see what happens for us women down the road to our shoulders/backs/ etc. I have been looking and have only found bits and peices but sounds like there is a issue. I believe you can not move large muscle without something happening to what they were connected to/what part they played.I was told the only problem would be if I was a down hill skier, its that last push, other wise thats all I would notice. Wrong!!!   If I knew now what I know ,I would do different, I thought there was a ?like gummy bear inplant ,not sure, but I would investigate that first, before I started moving mucles around. The problem is for me is I wanted breasts , I do have to say my breast turned out well, I do have a hard time finding bras that fir correctly, as I am fuller under my armpits ,and if I get a bra that helps pull that over I am in severe pain, crazy . All I can say if you are not in a hurry, check all your options out, I wish I had. Let me know if I can help in any way. jennyc

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